RAF Typhoon jets have operated alongside France's air force in a joint strike against an subterranean weapons facility in Syria employed by the IS group, per a report from the UK's MoD.
The facility, located using reconnaissance, was assessed as storing arms and explosives, the release indicated, and was located in mountains just north of the historic site of Palmyra in Syria's central region.
"Our aircraft utilized laser-guided Paveway IV weapons to hit a series of approach shafts leading to the depot... initial indications are that the objective was successfully hit," the MoD said.
There was no evidence of any harm to civilians in the strike late on Saturday and each participating jet returned to base without incident, the defence officials confirmed.
The Typhoon fighters were assisted by a Voyager tanker plane.
Daesh - referred to as Daesh - enforced jihadist rule over significant areas in Syria and Iraq before its territorial defeat in 2019.
"This strike underscores our UK leadership, and determination to operate in unison with our allies, to eliminate any resurgence of IS and their harmful and extremist ideologies in the area," UK Defence Secretary John Healey said.
RAF aircraft have conducted overwatch operations over Syria to "forestall any attempted comeback" of the group after its defeat at the climactic battle in Baghuz in the year 2019, the ministry said.
"I want to thank the personnel of the UK armed forces participating in this strike for their professionalism and their courage," Healey said. "They were part of thousands of UK service members deployed over the festive period. This mission, to remove dangerous terrorists who threaten our way of life, demonstrates how UK forces are prepared to act, continuously, protecting the UK at home and strong abroad."
During December, the American forces conducted what it termed a "massive strike" against Daesh sites in the country, after an attack resulted in the deaths of two US troops and a civilian linguist in Palmyra.
The UN estimates IS still has roughly 5-7 thousand militants in both countries.